当前位置： 科技成果
一、学术获奖情况
1.2018年度11月份，辽宁省科技进步二等奖，肿瘤转移相关因子在临床中的应用，排名第一，
2.（2018-J-2-53-R01）2016年度，中国抗癌协会科技奖一等奖，细胞周期调控异常在肿瘤发生发展中的作用和分子机制研究，排名第7，（K-1501-1-1-7）
3.2014年度，大连市科技进步二等奖，雷帕霉素联合顺铂抑制宫颈癌细胞的体外实验研究（排名第六），（2013J-2-26-06）
4.2013年度，辽宁省科技进步二等奖，主持项目：ALDOA等肺癌标记物的筛选及临床应用，第一完成人。（2013J-2-63-01）
5.2013年度，大连市科技进步一等奖，主持项目：肺癌诊断标记物的筛选及应用，第一完成人。（2012J-1-13-01）
6.2010年度，辽宁省科技进步三等奖，项目：中枢神经系统髓鞘再生机制及药物筛选平台的建立，第二完成人。（2010J-3-116-02）
7.2009年度，辽宁省科技进步三等奖，项目：放化同步治疗对脊髓损伤影响的实验研究，第二完成人。（2008J-1-14-02）
二、英文发表文章情况
通讯作者
1)Zhao Jie, Piao Xiangyu, Wu Yue,Liang Shanshan, Han Fang, Liang Qian, Shao Shujuan*, Zhao Dewei*.Cepharanthine attenuates cerebral ischemia/reperfusion injury by reducing NLRP3 inflammasome-induced inflammation and oxidative stress via inhibiting 12/15-LOX signaling.Biomedicine & Pharmacotherapy, 2020, 127:110151. IF=4.545
2)Jiang Ke, Liu Peng, Xu Huizhe, Liang Dapeng, Fang Kun, Du Sha, Cheng Wei; Ye Leiguang, Liu Tong, Zhang Xiaohong, Gong Peng, Shao Shujuan*, Wang Yifei*, Meng Songshu*, ,SASH1 suppresses triple-negative breast cancer cell invasion through YAP-ARHGAP42-actin axis.Oncogene, 2020, 39(27):5015-5030. IF=7.971
3)Guan Zhuzhu, Wang Yali, Wang Yu, Liu Xiaoxu, Wang Yan, Zhang Weimin, Chi Xinming, DongYan, Liu Xuefeng*, Shao, Shujuan*. Zhan Qimin*.Long non-coding RNA LOC100133669 promotes cell proliferation in oesophageal squamous cell carcinoma.Cell Proliferation, 2020, 53 (4): e12750. IF=5.753
4)Yin Zeli, Dong Chengyong, Jiang Keqiu, Xu Zhe, Li Rui, Guo Kun, Shao Shujuan*, Wang Liming * Heterogeneity of cancer-associated fibroblasts and roles in the progression, prognosis, and therapy of hepatocellular carcinoma.Journal of Hematology & Oncology.2019, 12(1): 101. IF=11.059
5)Bai Yuxin, Liu Xuefeng, Qi Xiaoyu, Liu Xuan, Peng Fang, Li Huimin, Fu Hailu, Pei Shimei, Chen liying, Chi Xinming, Zhang Liyuan, Zhu Xinbing, Song Yang, Wang Yang, Meng Songshu, Tao Jiang*, Shao Shujuan*. PDIA6 modulates apoptosis and autophagy of non-small cell lung cancercells via the MAP4K1/JNK signaling pathway.EBioMedicine. 2019, 42:311-325. IF=5.736
6)Pu chunwen, Huang Hui, Wang zhi dong, Zou wei, Lv Yuecai, Zhou Zhiyuan, Zhang Qiqi, QiaoLiang, WuFei, Shao Shujuan*. Extracellular Vesicle-Associated mir-21 and mir-144 Are Markedly Elevated in Serum of Patients With Hepatocellular Carcinoma. Frontiers in Physiology, 2018,9:930. IF=3.201
7)Dong Chengyong, Liu Ying, Jiang Keqiu,Wang Haibo, QU Weikun, Zhang Chi, Liang Rui, Gao Zhenming, Zhao Baofeng, Miao Qing, Shao Shujuan*, Wang Liming*. The Nogo-B receptor promotes human hepatocellular-carcinoma cell growth via the Akt signal pathway.Journal of Cellular Biochemistry, 2018, 119 (9): 7738 – 7746. IF= 3.448
8)Fu Hailu, Gao Huijun, Qi Xiaoyu, Zhao Lei, Wu Donghua,, Bai Yuxin, Li Huimin, Liu Xuan, Hu Jun*, Shujuan Shao*. Aldolase A promotes proliferation and G1/S transition via the EGFR/MAPK pathway in non-small cell lung cancer. Cancer Communications, 2018, 38(1):18. IF=3.822
9)Wu Donghua,Zhao Baofeng,Qi Xiaoyu,Peng Fang,Fu Hailu,Chi Xinming,Miao Qing*,Shao Shujuan*. Nogo-B receptor promotes epithelial-mesenchymal transition in non-small cell lung cancer cells through the Ras/ERK/Snail1 pathway. Cancer letters, 2018,4(18):135-146. IF= 6.508
10)Li Huimin, Lin Zhikun, Bai Yuxin, Chi Xinming, Fu Hailu, Sun Rui, Liu Meizi, Liu Xuan, Chen Liying, Shao Shujuan*.Sinomenine inhibits ovarian cancer cell growth and metastasis by mediating the Wnt/beta-catenin pathway via targeting MCM2. RSC Advances, 2017, 7 (79): 50017 - 50026. IF= 2.936
11)LongFei, Dong Chengyong, Jiang Keqiu, XuYakun, Chi Xinming, Sun Deguang, Liang Rui, Gao Zhenming, Shao Shujuan*, Wang Liming*, Melatonin enhances the anti-tumor effect of sorafenib via AKT/p27-mediated cell cycle arrest in hepatocarcinoma cell lines，RSC Advances，2017, 7 ( 34): 21342 - 21351. IF= 2.936
12)Sun Bing, Bai Yuxin, Zhang Liyuan*, Gong Linlin, Qi Xiaoyu, Li Huizhen, Wang Faming, Chi Xinming, Jiang Yulin, Shujuan Shao*,Quantitative Proteomic Profiling the Molecular Signatures of Annexin A5 in Lung Squamous Carcinoma Cells. PLOS ONE, 2016, 11 (9):.e0163622. IF= 2.806
13)Gao Huijun, Sun Bing, Fu Hailu, Chi Xinming, Wang Faming, Qi Xiaoyu, Hu Jun*, Shao Shujuan*. PDIA6 promotes theproliferation of HeLa cells through activating the Wnt/β-catenin signaling pathway. Oncotarget. 2016, 7(33):53289-53298. IF=5.168
14)Song Yang, Sun Bing, Hao Lihong, Hu Jun, Du Sha, Zhou Xin, Liu Lu, Gong Linlin, Chi Xinming, Liu Qiang, Shao Shujuan*. Elevated eukaryotic elongation factor 2 expression is involved in proliferation and invasion of lung squamous cell carcinoma.Oncotarget.2016,7(36):58470-58482. IF=5.168
15)Hao Lihong, Zhou Xin, Liu Shuqing, Sun Mingzhong, Song Yang, Du Sha, Sun Bing, Guo Chunmei, Gong Linlin, Hu Jun, Guan Hongwei, Shao Shujuan*. Elevated GAPDH expression is associated with the proliferation and invasion of lung and esophageal squamous cell carcinomas. Proteomics. 2015,15 (17)：3087-3100. IF=4.079
16)Sha Du, Zhuzhu Guan, Lihong Hao, Yang Song, Lan Wang, Linlin Gong, Lu Liu, Xiaoyu Qi, Zhaoyuan Hou, Shujuan Shao*. Fructose- Bisphosphate Aldolase A Is a Potential Metastasis-Associated Marker of Lung Squamous Cell Carcinoma and Promotes Lung Cell Tumorigenesis and Migration. PLOS ONE, 2014,9:(1)：e85804. IF= 3.234
17)Hao Lihong, Gong Linlin, Guo Yiping, Song Yang, Qi Xiaoyu, Guan Zhuzhu, Yang Xiaohan, Zhou Xin, Xue Liyan, Shao Shujuan*. Proteomics Approaches for Identification of Tumor Relevant Protein Targets in Pulmonary Squamous Cell Carcinoma by 2D-DIGE-MS.PLOS ONE, 2014, 9 (4):.e95121. IF= 3.234
18)Gong Linlin, Zhao Haoqi, Wang Lan, Sun Bing, Yu Lijun, Qi Xiaoyu, Zhou Xin, Zhang Liyuan, Guan Hongwei*, Shao Shujuan*.Upregulation of annexin A5 affects the biological behaviors of lung squamous carcinoma cells in vitro，Chinese Science Bulletin. 2014,59(28):3610-3620. IF=1.579
19)Benjamin Arko-Boham, Zhou Xin, Isaac Okai, Zhao Haoqi, Song Yang, Chi Xinming, Sun Bing, Hao Lihong, Zhang Liyuan, Liu Lu, Guan Hongwei, Shao Shujuan*. PRP19 upregulation inhibits cell proliferation in lung adenocarcinomas by p21-mediated induction of cell cycle arrest. Biomedicine & Pharmacotherapy, 2014,68 (4):463-470.IF=2.023
20)Okai Isaac, Wang Lan, Gong Linlin, Arko-Boham Benjamin, Hao Lihong, Zhou Xin, Qi Xiaoyu, Hu Jun, Shao Shujuan*, Overexpression of JAKMIP1 associates with Wnt/beta-catenin pathway activation and promotes cancer cell proliferation in vitro. Biomedicine & Pharmacotherapy. 2013,67(3):228-234. IF=2.108
21)Zhou Xin, Xue Liyan, Hao Lihong, Liu Shuqing, Zhou Fachen, Xiong Hai, Qi Xiaoyu, Lin Dongmei, Shao Shujuan*, Proteomics-based identification of tumor relevant proteins in lung adenocarcinoma. Biomedicine & Pharmacotherapy,2013,67(7):621-627.IF= 2.108
三、著作及教材
1)《组织学与胚胎学学习指导与习题集》，副主编，人民卫生出版社，2018年12月。
2)《组织学与胚胎学实验指导》，副主编，人民卫生出版社，2018年10月。
3)《组织学与胚胎学》第9版，副主编，人民卫生出版社，2018年8月。
4)《医学观念的更新与启示》，副主编，人民卫生出版社，2018年，2月。
四.教学论文
1) 宋阳；邵淑娟；初万江；周欣；迟鑫明；郝立宏.微课与PBL结合在胚胎学教学中的应用.解剖学杂志，2018.6期：755-756.
五.教学获奖及成果
1.研究生学位论文质量保障体系的构建，2018年，辽宁省普通高等教育教学成果奖（研究生类）一等奖。第一完成人，
2.建立研究生培养与招生计划管理联动机制、推进学科建设及供给侧结构性改革，2018年，辽宁省普通高等教育教学成果奖（研究生类）二等奖，第二完成人。