当前位置： 科技成果
（1）发表论文
1)Haina Wang#, Rui Wang#, Dan Huang#, Sihan Li#, Beibei Gao, Zhijie Kang, Bo Tang, Jiajun Xie, Fanzhi Yan, Rui Liang, Hua Li,Jinsong Yan. Homoharringtonine Exerts Anti-Tumor Effects in Hepatocellular Carcinoma through Activation of the Hippo Pathway. Frontiers in Pharmacology. 2021;12 (SCI, IF: 4.225)
2)闫金松，诊疗方案修订迫切需要伦理论证，医学与哲学，2020，41（21）656：9-13
3) Lou JC#, Hao YC#, Lin KF, Lyu YZ, Chen MW, Wang H, Zou Deyu, Jiang Xuewen, Wang RC, Jin D, Lam W.-F. Eric, Shao SJ, Liu Q,Yan JS*, Wang X, Chen Puxiang*, Zhang B*, Jin BL*. Circular RNA CDR1as Disrupts the p53/MDM2 Complex to Inhibit Gliomagenesis. Molecular Cancer, 2020, Accepted. (IF:15.302)
4) H Liu#, X Zheng#, C Zhang, J Xie, B Gao, J Shao, Y Yang*, H Wang*,J Yan*. Outcomes of haploidentical bone marrow transplantation in patients with severe aplastic anemia-II that progressed from non-severe acquired aplastic anemia. Frontiers of Medicine. 2020, Accepted.(IF:3.42)
5)黄亚男，谢佳君，周栋，张成涛，闫金松.化疗对男性淋巴瘤患者生育力影响的研究进展[J].中国医学前沿杂志(电子版).2020,12(9)：31-35.
6)Zhang Y#,Kang Z#,Lv D,Zhang X,Liao Y,Li Y,Liu R,Li P,Tong M,Tian J,Shao Y,Huang C,Ge D,Zhang J,Bai W,Wang Y,Liu Q,Li Z,Yan JS*. Longitudinal whole-genome sequencing reveals the evolution of MPAL.Cancer Genetics, 2019 Nov; 22(240):59-65. (IF:2.351)
7) Lu Y#,Yan JS#（Co-first author）, Xia L, Qin K, Yin QQ, Xu JT, Gao MQ, Qu XN, Sun YT, Chen GQ. 2-Bromopalmitate targets retinoic acid receptor alpha and overcomes all-trans retinoic acid resistance of acute promyelocytic leukemia.Haematologica, 2019 Jan;104(1):102-112.(IF:9.09)
8)H. Wang#,L. Mei#, Y. Deng, Y. Liu, X. Wei, M. Liu, J. Zhou, H. Ma, P. Zheng, J. Yuan, M. Li. Lactobacillus brevis dm9218 ameliorates fructose-induced hyperuricemia through inosine degradation and manipulation of intestinal dysbiosis.Nutrition. 2019;62:63-73.(SCI, IF: 3.734)
9) Y Lyu, J Lou, Y Yang, J Feng, Y Hao, S Huang, L Yin, J Xu, D Huang, B Ma, D Zou, Y Wang, Y Zhang, B Zhang, P Chen, K Yu, EW-F Lam, X Wang*, Q Liu*,J Yan*and B Jin*.Dysfunction of the WT1-MEG3 signaling promotes AML leukemogenesis via p53 dependent and independent pathways.Leukemia.2017 Dec;31(12):2543-2551. (IF:10.023)
10) D Huang, Y Yang, J Sun, J Shao, andJ Yan*. Annexin A2-S100A10 heterotetramer is upregulated by PML/RARα fusion protein and promotes plasminogen-dependent fibrinolysis and matrix invasion in acute promyelocytic leukemia.Frontiers of Medicine. 2017 Sep;11(3):410-422. (IF:1.863)
11) Caifeng Yue#,ZhiJie Kang#, Kexin Ai#, Duorong Xu, Jim Wu, Yujia Pan, JinSong Yan, Quentin Liu*.Virus infection facilitates the development of severe pneumonia in transplant patients with hematologic malignancies.Oncotarget. (2016)7:33. (IF:5.1)
12)Yan JS, Li YD, Liu SH, Yin QQ, Liu XY, Xia L, Lu Y*. The t(8;21) fusion protein RUNX1-ETO downregulates PKM2 in acute myeloid leukemia cells.Leuk & Lymphoma. 2016 Aug;58(8):1985-1988. (IF:3.09)
13) Kang ZJ, Liu YF, Xu LZ, Long ZJ, Huang D, Yang Y, Liu B, Feng JX, Pan YJ,Yan JS*, Liu Q*.The Philadelphia chromosome in leukemogenesis.Chin J Cancer. 2016 May 27;35:48.(IF:4.11)
14) Lu C, Liu X, Liu C, Wang J, Li C, Liu Q, Li Y, Li S, Sun S,Yan J*, Shao J*. Chlorpyrifos induces MLL translocations through caspase 3-dependent genomic instability and topoisomerase II inhibition in human fetal liver hematopoietic stem cells.Toxicol Sci. 2015 Oct; 147(2): 588-606. (IF:3.85)
15) Liu X, Wang J, Lu C, Zhu C, Qian B, Li Z, Liu C, Shao J*,Yan J*. The role of lysosomes in BDE 47-mediated activation of mitochondrial apoptotic pathway in HepG2 cells.Chemosphere. 2015 Apr;124:10-21. (IF:3.499)
16)Yan J, Chen X, Shao J*. A single course of ATRA plus arsenic trioxide reached a long-term survival in a patient with newly diagnosed acute promyelocytic leukemia: a suggestion for reduction of treatment courses.Eur.J.Haematol. 2013 Nov; 91(5):470-1.(IF:2.414)
17)Yan JS#, Wang KK#, Dong LM，Liu HC, Chen WQ, Xi WD, Ding QL, Kieffer N, P. Caen. J, Chen SJ, Chen Z, Xi XD*. PML/RARɑ fusion protein transactivates the tissue factor promoter through a GAGC-containing element without direct DNA association.Proc.Natl.Acad.Sci.U.S.A. 2010, 107:3716-3721.(IF:9.432)
18)Wang L#, Zhao WL#,Yan JS#(Co-first author) Liu P, Zhou GB, Weng ZY, Wu W L, Weng XQ, Sun XJ, Chen Z, Sun HD, Chen SJ*. Eriocalyxin B induces apoptosis of t(8;21) leukemia cells through NF-kappa B and MAPK signaling pathways and triggers degradation of AML1-ETO oncoprotein in a caspase-3-dependent manner.Cell Death&Differ. 2007;14:306-317. (IF:8.0)
（2）参编教材及获奖情况
参编教材《内科学》，高等教育出版社，闫金松，已出版（2017）；
参编教材《内科学》，人民卫生出版社，闫金松，待出版；
参编《医学科研概论》，科学技术出版社，闫金松，出版中。
获辽宁省人民政府科学技术进步奖二等奖，闫金松，（排名第9）
（3）专利
一种Ph-like急性淋巴细胞白血病融合基因及其应用和检测试剂盒， 申请号202011192505.4